ProQuad MMRV Live- measles, mumps, rubella & varicella (chicken pox) vaccine
Merck & Co., Inc. 2014
Vaccination against measles, mumps, rubella and varicella (chicken pox) for children 12-months-old through 12-years-old
For full package insert click HERE
Excerpt from package insert below
Ingredients:
-bovine calf serum
-chick embryo cell cultures
-human albumin, genetically-engineered
-hydrolyzed gelatin
-Measles virus vaccine Live from Enders weakened Edmonston strain
-media ingredients, buffered
-monosodium glutamate ‘(MSG)
-MMR-II (Measles, Mumps & Rubella virus vaccine Live)
-MRC-5 cells-residual components including DNA & protein
-Mumps virus ‘vaccine Live, Jerryl Lynn ‘(B level strain)
-neomycin
-Oka/Merck varicella virus
-potassium chloride
-potassium phosphate dibasic
-Rubella virus vaccine live, Wistar27/3, RA strain
-sodium bicarbonate
-sodium chloride (NaCl/table salt)
-sodium phosphate dibasic
-sorbitol
-sucrose
-Varicella virus vaccine Live(Oka/Merck strain of varcella-zoster)
-WI-38 human diploid fibroblasts
“ProQuad has not been evaluated, for its carcinogenic, mutagenic or teratogenic potential or its potential to impair fertility.”
“It is also not known whether ProQuad can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.”
United States Department of Agriculture determined other countries bovine products are risk-free of bovine spongiform encephalopathy (BSE).
Adverse Reactions ProQuad Live virus vaccine
diarrhea
eczema
exanthema, viral
fever
headache
herpes
injection site:
– bruising, ecchymoss, erythema, hemorrhage, pain, rash, soreness, swelling, tenderness
irritability
nasopharyngitis
rash: measles-like, rubella-like, varicella-like/vesicular, (not otherwise specified)
respiratory infection, upper
rhinorrhea
somnolence
vomiting
Post-Marketing Reports
Adverse reactions reported with post-marketing use of ProQuad and/or in clinical studies and/or post-marketing use of the component vaccines, and Varivax without regard to causality or frequency:
abdominal pain
agitation
anaphylacttoid reaction
anaphylaxis
apathy
aplastic anemia
arthralgia (usually transient and rarely chronis)
arthritis
ataxia
Bell’s palsy
blood disorder
bronchial spasm
bronchitis
candidiasis
cellulitis
cerebrovascular accident
chickenpox (vaccine strain)
convulsions, afebrile
dizziness
dream abnormality
ear nerve deafness
ear pain
edema: angioneurotic, eyelid, facial, peripheral
encephalitis
encephalopathy
encephalomyelitis, acute disseminated (ADEM)
epididymitis
epistaxis
erythema multiforme
extravasation
eye irritation
flatulence
Guillain-Barre syndrome
headache
hematochezia
Henoch-Schonlein purpura
herpes simplex
herpes zoster
hypersomnia
immune system disorders
impetigo
infection
influenza
injection site complaints:
–burning, discoloration, eczema, edema/swelling, hematoma, hive-like rash, inflammation, induration, lip abnormality, lump, papillitis, roughness/ dryness, stiffness, stinging, trauma, varicella-like rash, venipüncture site hemorrhage, vesicicles, warm sensation, warm to touch, wheal and flare.
Lymphadentis
lymphadenopathy, regional
lymphatic system disorder
measles, atypical
measles inclusion body encephalitis
meningitis, aseptic
mouth ulcer
musculoskeletal pain
myalgia
myelitis, transverse
nervousness
ocular palsies
optic neuritis
orchitis
pain: hip, leg, neck
panencephalitis, subacute sclerosing
panniculitis
paraesthesia
parototos
pneumonia
pneumonitis
polyneuritis
polyneuropathy
pruritus
pulmonary congestion
purpura
respiratory illness
retinitis
retrobulbar neuritis
rhinitis
seizure, febrile
seizures
sinusitis
skin induration
skin infection
sneezing
sore throat
Stevens-Johnson syndrome
sunburn
swelling
syncope
thrombocytopenia
tremor
wheezing
*”Deaths have been reported following vaccination with measles, mumps and rubella; vaccines. However a causal relationship has not been established in healthy individuals.”